I just came across an interesting article that suggests that discolouration of the toes could be one of the earliest signs of high cholesterol. High cholesterol – that often results from poor diet (and I should know!) – can lead to fatty deposits on the inside of arteries and this in turn can lead to blocked blood vessels. One of earliest symptoms, however, is a mottled purple colouration in the toes. For more information from the original article please click here.